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, , | Name = Glucose-6-phosphate dehydrogenase | HGNCid = 4057 | Symbol =
G6PD | AltSymbols =; G6PD1 | OMIM = 305900 | ECnumber = | Homologene =
37906 | MGIid = 105979 | GeneAtlas_image1 = PBB_GE_G6PD_202275_at_tn.png |
Function = | Component = | Process = | Orthologs =
}}Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose
phosphate pathway (see image), a metabolic pathway that supplies reducing
energy to cells (most notably erythrocytes) by maintaining the level of the
co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). The NADPH in
turn maintains the level of glutathione in these cells that helps protect
the red blood cells against oxidative damage.
G6PD converts glucose-6-phosphate into 6-phosphoglucono-?-lactone and is
the rate-limiting enzyme of the pentose phosphate
pathway.450px|center|Mechanism of G6PD
Glucose-6-phosphate dehydrogenase deficiency is very com
Discography not available
Videos not available